Андарин (САРМС, SARMs, S-4): особенности, эффекты, прием

Лучшие комбинации SARMs: можно ли использовать на ПКТ

На самом деле это достаточно распространенный вопрос. Можно ли использовать САРМы на ПКТ? Можно, но не все и не на всем периоде послекурсового восстановления. Я рекомендую воздержаться от Лигандрола, RAD-140, S-23 на ПКТ, особенно если у вас был тяжелый и продолжительный курс.

YK-11, Лаксогенин, Ibutamoren — частые гости ПКТ, которые никак не повлияют на восстановительную терапию, естественно при соблюдении разумных дозировок. При включении определенных SARMs в период восстановления я бы рекомендовал увеличить длительность самого цикла ПКТ, анализируя при этом все необходимые анализы, учитывая их динамику.

Andarine (S4) With Other SARMS

Andarine (S4) is comparable to other SARMs like RAD 140, Ostarine, and LGD 4033.

The 4 selective androgen receptor modulators all perform in a similar matter with the primary distinction being the strength and amount of suppression.

Therefore, Andarine (S4) is widely considered more powerful than Ostarine yet not as strong as LGD 4033.

Nonetheless, most consider Andarine one of the most powerful and effective SARMs available for purchase.

Andarine is a versatile SARM that not only helps you burn fat but build lean muscle.

For this reason, consuming multiple SARMs at the same time in a cycle (otherwise known as “stacking”) may help you reach your fitness goals faster.

Let’s review some of the popular options for stacking Andarine with other SARMs:

Stacking Andarine (S4) and RAD 140

Andarine (S4) stacks well with RAD 140.

RAD 140 Testolone is another potent and powerful SARM.

The SARM is especially popular with athletes and bodybuilders that need an efficient supplement for maintaining muscle mass and energy.

RAD 140 addresses low testosterone which is something Andarine fails to accomplish.

As a result, the two pair together nicely to create a weight stack for gaining lean muscle.

Stacking Andarine (S4) and 1-Andro

1-Andro is another top option for stacking with the powerful SARM.

The prohormone benefits protein synthesis, athletic performance, muscle growth, strength, and recovery.

Consequently, 1-Andro can help you bulk up with lean muscle and improved strength.

It’s recommended to continue the suggested dosage of 50mg of Andarine (S4) followed by 100-150mg of 1-Andro.

Stacking Andarine (S4), MK-677, & LGD4033

Individuals may stack Andarine with MK-677 as an alternative to RAD 140.

It’s important to note that MK-677 supports muscle growth while its close cousin – LGD4033 – is designed for fat loss.

Regardless, MK-677 and LGD4033 are reliable and versatile supplements that complement Andarine (S4).

There is no need to consider Post Cycle Therapy (PCT) with SARMs like MK-677 and LGD4033 as long as use discontinues after 12 weeks. 

Is it legal?

Legality in sport:

The use of Andarine is highly frowned upon in any competitive sport. The use of S-4 by a professional sports star is illegal and could attract either fines, suspension, or jail time. This is because it grants users an unfair advantage over their fellow sports stars. In 2008, the World Anti-Doping Agency (WADA) added Andarine to its list of prohibited drugs. Since then, athletes have been discouraged from using the drug.

Legality in diet:

It is illegal to use Andarine to formulate any diet supplement. The FDA and other such bodies are yet to certified the drug as “OK” for human consumption. It is, therefore, illegal to present it as a supplement.

Legality in medical-research:

It is legal to use Andarine for medical research purpose. This seal of legality is, however, lifted if the drug is capsulated or presented in a liquid form for human consumption.

Introduction

Andarine, commonly known as S4 in the market, comes under umbrella of wide group of drugs called SARM (Selective Androgen Receptor Modulator), but S4 is considered to be more potent and beneficial as compared to other similar SARMs like LGD-4033. It was first manufactured by GTX labs during its research aiming for treatments of senile- onset muscle wasting diseases like muscular dystrophy, osteoporosis and benign enlargement of prostrate.

It has shown promising results during animal trials and currently, numerous medical research teams are conducting various human trials to elicit more beneficial effects on skeletal muscle mass, strength and bone density. Even though S4 is yet to be prescribed by practitioners, it is widely included in body fitness regime of aspiring athletics. Moreover, the selectivity of the drug eliminates numerous side effects that traditional steroids bring.

SARMs: лучшие комбинации

В данной статье я хочу разобрать актуальную для многих тему — комбинации SARMs. Селективные модуляторы андрогенных рецепторов вплотную вошли в жизнь спортсменов. Не могу сказать, что они вытесняют стероиды, нет, это не так. Частота применения САРМов возрастает каждый год, учитывая и мою личную практику, и опыт.

Почему появился такой интерес к САРМс, а именно к их комбинациям? Все очень просто:

  • Достаточно несложная администрация применения данных соединений;
  • Возможность держать референтные значения уровней ЛГ и ФСГ (при совместном использовании антиэстрогенов);
  • Минимизация шанса получить тяжелые побочные эффекты;
  • Легальность покупки и использования большинства САРМов.

Считаю, что данных фактов достаточно, чтобы рассмотреть возможность включить комбинации из SARMs в свой цикл подготовки.

What is Andarine (S4)?

Andarine (S4) is a selective androgen receptor modular (SARM) designed to combat muscle and bone-wasting diseases.

Furthermore, there is evidence to support SARMs like Andarine against an enlarged prostate.2

Meanwhile, bodybuilders have started to tap into the potential of Andarine (S4) for weight loss.

The early results have been impressive as Andarine (S4) has transformed into one of the more powerful anabolics for burning fat.

Moreover, Andarine (S4) offers promising results for producing lean muscle mass and improving overall strength.

The benefits of Andarine (S4) are noteworthy:

  • Increases Lean Muscle
  • Improves Strength & Power
  • Fat Cutting & Weight Loss
  • Joint Healing Properties
  • Improves Recovery Time

The science behind SARMs is relatively new as the performance-enhancing agents were discovered in the late-1990s.

Nonetheless, the substance has gained notoriety among bodybuilders and those seeking to lose weight.3

SARMs are not anabolic steroids but, rather, serve as synthetic ligands that bind to androgen receptors (ARs).4

Therefore, SARMs may stimulate anabolism which is necessary to improve muscle mass and strength.5

Andarine (S4) interjects 50mg of the SARM for daily supplementation.

Notwithstanding, it’s important to note that Andarine has not yet been approved by the U.S. Food and Drug Administration (FDA).

Unfortunately, selective androgen receptor modulators (SARMs) are among many other alternative health products that require more government oversight to reach a firm conclusion on its benefits.

Be that as it may, there is growing research that supports the use of Andarine for improved athletic performance and body composition.

Andarine (S4) Side Effects

The manufacturer of Andarine (S4) claims that the SARM does not feature any serious side effects.

They warrant this reassurance with valid third-party testing that verifies the potency and purity of the substance in each bottle.

Nonetheless, clinical research still remains limited regarding Andarine and other SARMs thanks to FDA rejection.

There is some concern from outside sources that Andarine may impair vision or suppress testosterone levels.

While true that Andarine does suppress the natural production of testosterone these levels are known to return back to normal within a few weeks of completing the cycle.

It’s why users should take note of the recommended cycle stage for Andarine (S4) which is a maximum of 8-12 weeks.

Secondly, there are a few vision concerns associated with Andarine yet the legitimacy remains questionable.

There is no direct correlation between the substance and any long-lasting or permanent vision problem.

Regardless, individuals should consider speaking with a physician before starting any new type of supplementation.

It’s especially important if you already take other prescribed medications or have serious health concerns.

Andarine is not approved by the FDA which makes it ripe for scammers to take advantage of on the black market.

Thus, we suggest considering purchasing only through a reliable manufacturer like GTX Pharmaceuticals.

Andarine Benefits

Andarine is a very versatile and you can use it for cutting, recomposition or bulking.

Cutting

Andarine has similar properties to “cutting” steroids such as Winstrol and Anavar. By binding to the androgen receptor, Andarine increases fat oxidation. It also decreases lipoprotein lipase (LPL), an enzyme that causes lipid accumulation.  This sarm S4 is often compared to Winstrol since it increases vascularity and promotes a very nice “quality” hard look to the user’s muscles with no water retention.

Another great benefit to including Andarine in a cutting protocol is that it’ll prevent the loss of muscle mass while in a calorie deficit. One of the most disheartening outcomes of cutting is the loss of hard earned muscle mass. As S4 has both anabolic and androgenic effects in muscle tissue, it will not only help with fat loss, but maintain and even increase muscle mass when cutting.

Andarine also doesn’t cause the painful lower back and calf pumps associated with other popular steroids/prohormones.

Recomposition

Recomping is when you lose fat and gain muscle at the same time. In fact, this is what the majority of users are looking for. Andarine is a favorite when recomping due to its nutrient partitioning effects. One of the most common SARMS cycles is the SARMS triple stack which is a combination of Ostarine (MK2866), Andarine (S4) and Cardarine (GW501516).

Bulking

Due to its androgenicity in muscle tissue, Andarine will promote increases in strength without bloat or water retention. The weight gain from S4 may not be that great in comparison to bulking steroids such as deca or Superdrol, but the lean mass and strength gained during the cycle is kept and not lost after the cycle.

Pharmacologic activity of Andarine on Muscle Growth & Prostate Size

Dosage

Among all the SARM, Andarine has one of
the shortest half-life – about 3 hours. It is recommended to use between
25mg-50mg daily to minimize the side effects. Usage should not exceed 12-16
weeks, and it is advisable to split dosage into three for a better result.

It is recommended that users do not go
below 6 weeks and not exceed 16 weeks. The body stops responding to the drug
after 16 weeks. Using the drug after then would be considered as wastage. If
the drug is discontinued after less than 6 weeks, you will not get the desired
result.

You should use the drug 5 times in a
week and then leave a gap of two days between dosage to limit side effect.

How To Use

Cutting Cycle

Week Andarine

(S4)

Cardarine (GW501516)HCGenerate ES
150mg/day (25mg AM 25mg PM)20mg/day
250mg/day (25mg AM 25mg PM)20mg/day
350mg/day (25mg AM 25mg PM)20mg/day
450mg/day (25mg AM 25mg PM)20mg/day
550mg/day (25mg AM 25mg PM)20mg/day
650mg/day (25mg AM 25mg PM)20mg/day
750mg/day (25mg AM 25mg PM)20mg/day
850mg/day (25mg AM 25mg PM)20mg/day
95 tablets/day
105 tablets/day
115 tablets/day
125 tablets/day

Recomposition Cycle

Week Andarine

(S4)

Cardarine (GW501516)Ostarine (MK2866)HCGenerate ESClomid
150mg/day (25mg AM 25mg PM)20mg/day25mg/day
250mg/day (25mg AM 25mg PM)20mg/day25mg/day
350mg/day (25mg AM 25mg PM)20mg/day25mg/day
450mg/day (25mg AM 25mg PM)20mg/day25mg/day
550mg/day (25mg AM 25mg PM)20mg/day25mg/day
650mg/day (25mg AM 25mg PM)20mg/day25mg/day
750mg/day (25mg AM 25mg PM)20mg/day25mg/day
850mg/day (25mg AM 25mg PM)20mg/day25mg/day
95 tablets/day25mg/day
105 tablets/day25mg/day
115 tablets/day25mg/day
125 tablets/day25mg/day

What the Research Says About Andarine (S4)

Andarine attaches to proteins in the body known as androgen receptors (ARs).

Selective Androgen Receptor Modulators (SARMs) act as performance-enhancing agents that direct muscles and bones to grow.

However, unlike steroids (which operate in a similar manner), Andarine does not bind to all androgen receptors and therefore avoids the nasty side effects.

The manufacturers of Andarine (S4) have the SARM undergo third-party testing, despite lacking FDA oversight.

Meanwhile, Andarine is gaining clinical support, especially when treating issues related to the prostate.7

All in all, there is research that indicates Andarine produces significant increases in muscle tissue and bone density.

Regardless, research will remain limited until the FDA relaxes its stance on Andarine and other SARMs.

Side effects, dosages and half life

SARMs have fewer side effects than anabolic steroids because of their selectivity. Side effects such as male breast enlargement, elevated blood pressure, hair loss, acne, or the appearance of masculine traits in women (these can be observed in people who use anabolic steroids) are impossible from SARMS. Also, SARMS are not liver toxic and do not affect cholesterol levels, blood pressure, your kidneys or your prostate.

However, users may experience a suppression in luteinizing hormone (LH) and follicle stimulating hormones (FSH) from Andarine usage. LH and FSH promote the production of reproductive hormones in men and women, and suppression could suppress normal estrogen/testosterone levels. However, it is unknown if and how much S-4 would actually suppress testosterone/estrogen production in humans. It suppressed LH and FSH in castrated rats but had no effect in normal male rats.

Besides suppression, the most frequent user-reported side effects are visual issues such as seeing a yellow tint and difficulty adjusting to night vision. The S-4 molecule binds to the retina in the eye which causes a yellow tint to be seen. This generally occurs at night, especially when switching from a dark to lightened area. However, the side effect is not serious and will disappear immediately after the drug’s usage has been discontinued.

Buy Andarine

The recommended dosage of Andarine for men is 50 milligrams (mg) per day for 8- 12 weeks. However, women should use half that dosage. The half-life of S4 is only 4 hours so users should split up their daily dosage into and AM and PM dosage. In fact, it does not matter if you take S4 on an empty stomach or with food. Also, since Andarine is not a stimulant, taking it near bedtime will not affect sleep.

Benefits

Since a large number of researches are
going around regarding S4, varieties of benefits have been reported world-wide.
Some of these are listed below.

  1. Bioavailability of Andarine is very high as opposed to other SARMs. This means Andarine is very potent and a smaller dose is enough to exhibit significant benefits. Moreover, according to research journals, Andarine doesn’t undergo aromatization (the process of conversion of testosterone to estrogen). This eliminates the risk of estrogenic side effects like water retention, hair loss, gynecomastia.
  2. S4 increases the release of testosterone, and by doing so it helps to increase the energy level, improving stamina and strength.
  3. Improvement in metabolic activity enhances the increase in muscles and weight loss.
  4. Even though reports have suggested there is a slight suppression in natural testosterone levels, there is no related user report on this.  The suppression could be potentially due to its anabolic activity but researchers claim that lower doses don’t cause severe hypothalamic pituitary suppression and there is no need for a PCT (post cycle therapy).

Uses of Andarine

Andarine is mostly used for cutting,
bulking and recomposing.

Cutting:

using Andarine increases fat oxidation in the body and it reduces lipoprotein lipase in the body. S-4 ensures that the body does not lose its muscle mass during a calorie deficit. Cutting cycle takes about 12 weeks.

Bulking:

Just as the name implies, bulking means strength without needless inflation and water retention. The bulking effect of Andarine is not always too exceptional, but it ensures that the body does not lose any of the strength it gathered throughout the cycle.

Recomping:

This is the process of striping the body of fat and increasing muscle mass at the same time. Andarine promotes lean body mass and increases body functionality.

Andarine (S4) Dosage and Cycle Instructions

The manufacturers of Andarine (S4) suggest a daily dose of 50mg.

It’s noted that this dosage appears to demonstrate the best results for burning fat and building muscle mass.

More importantly, the 50mg dosage does not appear to produce any serious side effects (more information, below).

It’s important to remember to split the daily consumption between two separate doses of (25mg).

It’s recommended that you take half of the dose in the morning and the other half in the evening.

Why?

Andarine (S4) features a half-life of approximately 6-8 hours.

The producers of Andarine (S4) do not recommend using the SARM in a cycle longer than 8-12 weeks.

The good news is that SARM does not require Post Cycle Therapy (PCT) with the correct dosage and cycle length.

In general, a PCT is necessary to assist the body to recover to a natural state following the weight stack cycle.

Andarine (S4) is available in the following flavors: Sour Apple, Strawberry Lemonade, Elderberry, and Unflavored.

Lastly, Andarine will show up on a drug test, so keep that in mind if you play a collegiate sport or are joining the military.6

Chapter 6. Side effects

Andarine (s-4) does not aromatize into estrogen at all, is not androgenic, and is only slightly suppressive of the pituitary glands.  Due to the suppression, a mini-post cycle therapy is recommended to help with recovery.  A simple way to do it is use hcgenerate ES for 4-8 weeks.

The one side effect that Andarine (s-4) has that makes it very unique is that it will attach slightly to androgen receptors which affect our eyes.  What happens is you will notice a yellow tint when changing different lit rooms, or when waking up in the morning.  This is not universal and is also dependent on the dosage you are using.  Also, keep in mind it is temporary, and once you stop using it the issue will go away after a few days.

What is Andarine (S4)?

Andarine is a selective androgen receptor modulator (SARM) originally developed to treat muscle wasting diseases and osteoporosis. It has shown promise in preliminary animal studies where it effectively increased bone density, muscle mass, and strength. It is currently undergoing human clinical trials.

SARMs are drugs that bind to the androgen receptor (AR), but are selective in their actions. This prevents them from causing unwanted side effects such as hair loss, gynecomastia or water retention. Moreover, Andarine is regarded as having high oral bioavailability and great muscle building properties. Phase one human trials with this drug have reportedly been successful but no studies have been published.

Side effects of Andarine

Regular use of Andarine will always attract side effects. The good news is, none of the side effects are permanent. It is also important to note that the use of S-4 follows after the law of diminishing returns. This means that after some time of consistent use, it becomes less effective because your body has developed a tolerance to it.

Andarine is heavily linked to depression and vision changes. This is the major side effect of S-4. Andarine attaches itself to the receptor in the eyes, and this causes vision changes and difficulty in distinguishing colors. The eyes also find it difficult to adjust to sunlight.

Adverse Effects

Even though the suppressive action on pituitary gland of Andarine is not prominent, like any other medicinal compounds, this drug also reported to have milder side effects. However, male breast enlargement, raised blood pressure, hair loss, appearance of masculine traits in females and hepatotoxicity are not seen with SARMs, owning to their selective action on muscles and bones.

With Andarine, users have reported to issues of seeing small yellow dots with problems to vision in dim light. This is because S4 molecule binds to receptors in retina. Users usually note this at night, while moving from dark to bright areas. However, this effect is reversible and immediately disappears when users stop the drug.

Uses

Role in fitness industry

S4 is very popular among athletics for ‘cutting’ and ‘bulking’ purpose. Even with less consumption of calories, users have shown to increase strength and muscle mass. Within short span of time, you can increase your training hours in the gym without feeling fatigue. Andarine promotes fat oxidation and reduces lipoprotein lipase activity. This decreases fat accumulation and hence helps maintain their weight but converting the stored fats into new muscle tissues. These are the characteristics desired by fitness freaks, athletics and bodybuilders. Some might want to stack S4 with other SARMs for synergic action.

Effects on reproductive system

Studies have shown S4 to be selective to prostrate and could be clinically beneficial in treating benign prostrate hyperplasia (commonly occurring in elderly men).  S4 does this by inhibiting dihydrotestosterone to bind to the androgen receptors and helps in treatment of BPH.

Treatment of osteoporosis and degenerative diseases.

Owing to its ability to prevent muscle wasting, S4 could be a possible option for treating senile-onset osteoporosis. This is a disease seen in elderly post-menopausal women where pathological fractures are very common. There is an imbalance in bone formation and bone degeneration. Andarine increases bone mineral density and improve the bone matrix, increasing strength and stamina.

Aids in weight loss

In today’s
modern world, obesity is a main concern because of unhealthy life styles
choices and lack of physical activity. When sedentary lifestyle is prevailing,
exercise is becoming old-fashioned. Even with balanced low calorie diet, promoting
fat loss still remains an exhausting task. With Andarine, there is a boost in
metabolism of body which not only promotes fat loss but gain of lean muscle
mass, significantly provide the perfect body shape which most professionals,
including athletics, models, bodybuilders desire.

Conclusion

What is there not to like about Andarine (S4)?

The selective androgen receptor modulator (SARM) is a much safer and more effective alternative to traditional steroids.

The SARM binds to androgen receptors critical to strengthening muscle tissue and bone density.

As a result, you will not only burn unwanted fat but gain healthy muscle mass.

Additionally, users of the SARM notice improvements in recovery time with a more defined body that attracts the opposite sex.

Unfortunately, SARMs like Andarine lack federal approval from the FDA which is too bad considering all the recent traction weight stack supplements like this are earning from satisfied customers.

Andarine (S4) is most effective when you consider combining with other SARMs for the ideal weight stack.

Ultimately, Andarine (S4) is one of the most powerful and versatile SARMs on the market.

References

  1. Rabijewski M, Papierska L, Piątkiewicz P. The Relationships between Anabolic Hormones and Body Composition in Middle-Aged and Elderly Men with Prediabetes: A Cross-Sectional Study. J Diabetes Res. 2016;2016:1747261. doi:10.1155/2016/1747261 (source)
  2. Gao W, Kearbey JD, Nair VA, et al. Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia. Endocrinology. 2004;145(12):5420-5428. doi:10.1210/en.2004-0627 (source)
  3. Hansson A, Knych H, Stanley S, Thevis M, Bondesson U, Hedeland M. Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high-resolution mass spectrometry. Rapid Commun Mass Spectrom. 2016;30(7):833-842. doi:10.1002/rcm.7512 (source)
  4. Solomon ZJ, Mirabal JR, Mazur DJ, Kohn TP, Lipshultz LI, Pastuszak AW. Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications. Sex Med Rev. 2019;7(1):84-94. doi:10.1016/j.sxmr.2018.09.006 (source)
  5. Bhasin S, Jasuja R. Selective androgen receptor modulators as function promoting therapies. Curr Opin Clin Nutr Metab Care. 2009;12(3):232-240. doi:10.1097/MCO.0b013e32832a3d79 (source)
  6. Starcevic B, Ahrens BD, Butch AW. Detection of the selective androgen receptor modulator S-4 (Andarine) in a doping control sample. Drug Test Anal. 2013;5(5):377-379. doi:10.1002/dta.1466 (source)
  7. Gao W, Kearbey JD, Nair VA, et al. Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia. Endocrinology. 2004;145(12):5420-5428. doi:10.1210/en.2004-0627 (source)

See Also

4.8 out of 5 (76 Ratings)

Andarine, or S4, is a SARM that claims to provide numerous benefits, but does it really work? Find out in our exclusive review.

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Лучшие комбинации SARMs для набора мышечной массы и сушки

С вашего позволения, первоочередно опишу комбинации, которые мы благополучно использовали и используем с моими атлетами, так сказать реальный опыт и отзывы.

Повторюсь, масса или сушка — это вопрос исключительно питания, выполнения грамотно построенного тренировочного плана и фактора восстановления.

При условии грамотных тренировок, питания и отдыха, рекомендуем присмотреться к следующим комбинациям SARMs:

  • RAD-140 + Laxogenin;
  • Mastorin (S-23) + YK-11 + RAD-140;
  • Ligandrol + RAD-140.

Также были и другие вариации, но все же хочу остановиться пока на вышеперечисленных

Не буду заострять внимание на каждом отдельном препарате, описание САРМов есть в разделе SARMs, опишу общую картину

RAD-140 + Laxogenin

Довольно распространенная комбинация, которая при дефиците калорий даст хороший жиросжигающий эффект, а при профиците калорий принесет качественную мышечную массу. При этом профицит должен быть разумным, нельзя кушать все что попало, помните про это.

Тут есть важный момент, а именно снижение уровней тестостерона. Как избежать этого? Правильно использовать совместно с антиэстрогенами или экзогенным тестостероном любого эфира, который вам нравится.

Если вас тревожит ваш уровень фертильности, то ваш вариант однозначно САРМ + Антиэстрогены. В случае, если потомство в этот период вас не интересует — вы спокойно можете включить в ваш цикл тестостерон с обязательным последующим послекурсовым восстановлением (ПКТ).

Обязательно до начала курса сдайте все необходимые анализы, советую изучить данную статью: руководство по первому курсу стероидов.

Следите за показателями здоровья на курсе в особенности: печеночные ферменты, липидный профиль, эстрадиол, пролактин, тестостерон общий, общий анализ крови, список может расширяться в зависимости от выбранных препаратов и их рабочих дозировок.

Что касается длительности такого стека, то я бы не делал его более 8 недель. При необходимости такую комбинацию можно продлить, а можно перейти на другие комбинации САРМов. Рабочие дозировки SARMs и тестостерона подбираются индивидуально и зависят прежде от ваших целей и амбиций и, само собой, здоровья!

Mastorin (S-23) + YK-11 + RAD-140

Данная комбинация достаточно серьезная и при грамотном использовании даст вам хороший прирост мышечной массы. Данную комбинацию актуально использовать атлетам, которые ранее проводили курсы, однако данный курс подходит и для новичков, просто нужно тщательно следить за анализами и не превышать разумные дозировки, а не полагаться на волю судьбы.

Масторин используется также для профилактики остеопороза, повышает минерализацию костной ткани.

Очень часта к данным САРМам добавляют гормон роста — это не только ускоряет липолиз, но и благотворно влияет на мелкие травмы. К данной схеме уместно добавить Тестостерон или кломид. Дозировки зависят от основных параметров спортсмена.

Если говорить за длительность такого курса, то имеет смысл делать его не более двух месяцев с последующим перерывом или переходом на новый стек препаратов

Внимательно относитесь к сдаче и корректировке анализов —  это очень важно

Ligandrol + RAD-140

Сразу хочу предупредить: начинайте данную схему с минимальных дозировок Лигандрола, не превышайте допустимые дозировки. В такой стек я настоятельно рекомендую включить тестостерон или антиэстроген, например Кломифен цитрат (Клостилбегит в аптеке).

Обратите внимание, что Лигандрол может резко повысить значения печеночных ферментов, если это произойдет, следует снизить дозировку Лигандрола либо вообще исключить его из вашего цикла. Не превышайте допустимую длительность применения данного цикла — не более 30 дней применения Лигандрола

Не стоит применять Лигандрол более месяца, в последствии советуем заменить его на другой продукт, например на AC-262 аккадин. Аккадин достаточно хороший селективный модулятор, который не токсичен для печени как Лигандрол. Кстати Аккадин часто применяется на стероидных курсах, где проявляет способность купировать последствия от высокого дигитротестостерона.

Chapter 5. Use in athletics

There are many ways you can utilize Andarine (s-4) to your advantage.  You are most certainly able to run it solo, but many athletes like to use it as part of a stack for maximum synergy.  You want to keep the cycle length to around 8-12 weeks on average, and not exceeding 16 weeks.  Here are some ideas depending on your goals:

Section 1. Powerlifters:

Andarine (s-4) mysteriously is one of the best SARMs (selective androgen receptor modulators) for strength.  I like to stack 50-75mgs per day with 10mgs per day LGD4033 (Anabolicum). For those who use anabolic steroids, you can also add it in at the same dosage.  A good stack is Andarine (s-4) + Trenbolone at 250mgs per week, you should hit personal records on that cycle.

Section 2. Those seeking to lose body fat:

Andarine (s-4) also seems to work well for cutting down body fat while in a deficit.  A popular cutting stack is using 50mgs a day + 20mgs per day of Cardarine (GW501516).  Those who use steroids can add in Anavar at 50mgs per day or Winstrol at 25mgs per day.

Section 3. Bodybuilders trying to recomp:

Andarine (s-4) is also great at adding lean muscle mass while also losing body fat.  This concept is called “recomping the body” and it is very difficult to do without the help of compounds like these.  A good stack for this would be Andarine (s-4) at 50mgs per day + 20mgs per day of Cardarine (GW501516) + 10mgs per day LGD4033 (anabolicum).  Those who use steroids can use the same dosage of Andarine (s-4), along with 500mgs a week of Primobolan + 175mgs a week of Testosterone Cypionate.

Another good reason to always use Andarine (s-4) with your anabolic steroid stack is that it will help prevent head hair loss and enlarged prostate.  If you notice yourself peeing a lot on cycle it probably means your prostate is getting too big, which is not a good thing.

Chapter 4. Comparing to anabolic steroids

Andarine (s-4) is very mild, so do not expect crazy changes in weight, strength, and aggression like you would from using anabolic steroids.  However, the benefits of using it are stronger bones, lean muscle mass, and mild strength gains.  Users also say, when properly stacked, it is great for fat loss too while in a carbohydrate and calorie deficit.

Another benefit is that it does NOT give you the following side effects, while anabolic steroids CAN:

  1. Enlarged prostate
  2. Shedding of head hair
  3. Aggression issues
  4. Liver and kidney strain
  5. Heart strain
  6. Mood swings
  7. Insomnia
  8. Sometimes permanent dysfunction of reproductive health
  9. The shutdown of the pituitary glands
  10. Estrogenic issues like water retention and gynecomastia

Chapter 3. Working in the body

Just like every other SARM (selective androgen receptor modulator), Andarine (s-4) works by attaching to androgen receptors selectively.  According to the studies, we also know that it is milder than others in its class because it is a partial agonist of the androgen receptor. However, don’t let that fool you into thinking it won’t still give you some solid results.

Another cool thing Andarine (s-4) does is that studies showed it had anti-DHT (dihydrotestosterone) effects in the body.   This means it will block sex hormones which cause things like the shedding of head hair and enlarged prostate (similar to 5a reductase inhibitors like finasteride and dutasteride).   However, and this is huge, it does NOT carry over the negative side effects of those nasty drugs.  So you do not have to worry about libido problems and feeling crappy.

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